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Progesterone 57-83-0 pregn-4-ene-3,20-dione P4 progestogen Prontogest

Categories Pharmaceutical Raw Materials
Brand Name: Health Herb
Model Number: USP EP
Certification: COS
Place of Origin: CHINA
MOQ: 5KGS
Price: Negotiable
Supply Ability: 50MT/MONTH
Delivery Time: 7 DAYS
Packaging Details: 20KGS/DRUM, 25KGS/DRUM, 8KGS/DRUM
Name: Progesterone
CAS: 57-83-0
Appearance: White powder
Standard: USP
Assay: 99%
Source: Synthetic
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    Progesterone 57-83-0 pregn-4-ene-3,20-dione P4 progestogen Prontogest

    We supply good quality product Progesterone.


    Introduction


    Progesterone (abbreviated as P4), also known as pregn-4-ene-3,20-dione, is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid.


    Application


    The use of progesterone and its analogues have many medical applications, both to address acute situations and to address the long-term decline of natural progesterone levels. because of the poor bioavailability of progesterone when taken orally, many synthetic progestins have been designed with improved oral bioavailability and have been used long before progesterone formulations became available.

    Progesterone is a female progesterone hormones important for the regulation of ovulation and menstruation. women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; and treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (pms). progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. if estrogen is given without progesterone, estrogen increases the risk of uterine cancer.


    Basic information


    CAS NO.57-83-0
    Molecular FormularC21H30O2
    Molecular Weight314.47
    EINECS200-350-6
    SpecificationUSP36
    Special Spec.Micronized: 100% pass 10micron; Sterile, Pyrogen Free.
    Characteristicscrystalline powder
    LevelPharmaceutical Grade
    Total impuritiesNMT 1.5%
    Packing20kg/drum

    COA


    TestsStandardResults
    AppearanceA white or almost white crystalline powder or colourless crystalsA white crystalline powder
    Identification

    A: IR

    B: TLC

    Conforms
    Specific rotation+186~+194°+190°
    Related substance

    Impurity B≤0.2%

    Impurity C≤0.3%

    Impurity D+E≤0.15%

    Impurity H≤0.5%

    Impurity I(Sum of the 2 epimers)≤0.6%

    Impurity J≤0.15%

    Impurity K≤0.15%

    Impurity L≤0.15%

    Impurity M≤0.15%

    Individual unidentified impurities≤0.10%

    Sum of impurities other than H≤1.0%

    Impurity B<0.05%

    Impurity C 0.11%

    Impurity D+E<0.05%

    Impurity H<0.05%

    Impurity I<0.05%

    Impurity J<0.05%

    Impurity G<0.05%

    Impurity L<0.05%

    Impurity M<0.05%

    Individual unidentified <0.05%

    Total impurities 0.1%

    Loss on drying≤0.5%<0.1%
    Assay97.0~102.0% (dried substance)100%
    Fineness95%≤10um95%<7.2um
    ConclusionIt conforms to EP8


    Quality Progesterone 57-83-0 pregn-4-ene-3,20-dione  P4 progestogen Prontogest for sale
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