Human Growth Hormone Peptide 1mg/vial Lean Muscle Building IGF-1
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a
synthetic protein and lengthened analogue of human insulin-like
growth factor 1 (IGF-1).It differs from native IGF-1 in that it
possesses an arginine instead of a glutamic acid at the third
position in its amino acid sequence ("arginine 3"), and also has an
additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN)
("long"), for a total of 83 amino acids (relative to the 70 of
IGF-1). The consequences of these modifications are that IGF-1 LR3
retains the pharmacological activity of IGF-1 as an agonist of the
IGF-1 receptor, has very low affinity for the insulin-like growth
factor-binding proteins (IGFBPs), and has improved metabolic
stability.As a result, it is approximately three times more potent
than IGF-1,and possesses a significantly longer half-life of about
20-30 hours (relative to IGF-1's half-life of about 12-15 hours).
Unit Size: 1mg
Appearance: Lyophilized White Powder
CAS NO: 946870-92-4
Synonyms: Insulin-Like Growth Factor-I LR3
Storage: IGF-1 LR3 is stable at room temperature for 90 days.
Why is this IGF-1 important for a bodybuilder or athlete? Let’s
take a look at the list:
Helps regulate fat for use as energy, resulting in fat loss.
Contributes to anti aging. As we get older, IGF-1 production slows
down and this results in cell reduction. Low levels of IGF-1 are
linked to heart failure, lower brain cell regulation and neuron
function. Not to mention muscle tissue breakdown.
Helps to increase nutrient shuttling (protein synthesis).
Increases regenerative functions of nerve tissues.
Boosts the ability to cause hyperplasia in muscle cells resulting
in fuller muscle tissue.
So increased potency, increased muscle retention... what else?
Well it increases the effectiveness of an anabolic cycle, this is
because of a very unique quality of igf-1-lr3, you see IGF-1 acts
on several different tissues to enhance growth. IGF1 belongs in the
’superfamily’ of substances known as ‘growth factors,’ along with
epidermal , transforming; platelet derived fibroblast, nerve, and
ciliary neurotrophic growth factors. None of the other factors have
any bearing on exoskeletal tissue incidentally; however, these
agents all have in common the ability to stimulate cell division,
known as mitogenesis, and cell differentiation. Meaning That In the
case of IGF1 which does act on muscle tissue it will initiate the
growth of new muscle fibers, and subsequently new receptors for
testosterone. Many Users on forums have unanimously concluded that
it enhances cycles of steroids significantly. They also seem to be
adamant about its ability to reduce fat and improve vascularity a
Another surprising effect that remains largely unexplained is that
it actually Reverses testicular atrophy. Testicles if shrunken will
return to “full swing” as it were even in the middle of a steroid
cycle. If not shrunken they will not shrink during the cycle. This
may explain partially why gains are kept after the cycle. The
increased circulating levels of IGF seem to prevent shrinkage and
allow for increased LH output post cycle.
How Does IGF-1 Work?
Of course, the liver can synthesize IGF-1 and it can package it
with various binding proteins. It then makes it ready for transport
into the blood. There are a couple of different variants when it
comes to IGF-1 and these are all produced in the muscle. One of
them is called the mechano growth factor and this plays a role in
how much muscle you can gain over a set period of time. It works by
spurring the activity of other muscles and these are called
satellite cells. These help to repair any damaged muscles and this
is what you would normally experience when you do exercise or when
you train. In fact, if you do a lot of weight training then you may
stimulate the release of IGF-1 in your muscle but when you take a
look at myostatin, you’ll find that this prevents muscle from
growing and this is all because of the satellite-cells and their
Differences Between LR2 IGF-1 and LR3 IGF-1:
While lr2 igf-1 and lr3 igf-1 are structurally and molecularly
similar, the two should not be confused. A primary difference is r3
igf-1 is predominately found in adult animals while 1gf-1 is found
in younger animals still developing the body systems. Igf-1 has the
most effect on the growth of muscle tissue as well as the repair of
the tissue. It has a very short half-life, lasting only about 20
The lr3 igf-1 peptide was developed for research over the long term
as it helps to prevent the binding proteins in the blood from being
deactivated. Igf-1 for sale in laboratory testing allows the
half-life of the peptide to be extended up to 20 hours and enables
more effective testing with the longer period of time. Experiments
which require more than one round will benefit from the longer
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